14:I[94367,["/_next/static/immutable/chunks/4370mg0uq-myq.js","/_next/static/immutable/chunks/0q7ni_ir0mogv.js","/_next/static/immutable/chunks/0q9_4lzwjwc3f.js","/_next/static/immutable/chunks/1p8rnjckwz-06.js","/_next/static/immutable/chunks/3zikwth1q5z_-.js","/_next/static/immutable/chunks/0eigul57_x91p.js","/_next/static/immutable/chunks/3r0kxtkfnobr8.js","/_next/static/immutable/chunks/260mvqou7a4l3.js","/_next/static/immutable/chunks/14bkwvgoktej3.js"],"NewsDetailPage"] 15:T14be,

India is moving towards more personalised bone-graft manufacturing with support from the Technology Development Board (TDB) and the Department of Science & Technology (DST) for the commercialisation of 3D-printed, patient-specific bone grafts. The project is being undertaken by Ceramat Private Limited, Palghar, Maharashtra, and focuses on developing standard and customised grafts using domestically produced bioceramic materials.

The project, titled “Calcium Phosphate-based Standard and Customised Patient-Specific Grafts by 3D Printing via Digital Light Processing Technique and Extrusion-based Equipment", seeks to combine advanced additive manufacturing with calcium phosphate-based biomaterials. The objective is to move beyond conventionally manufactured bone grafts towards digitally designed products that can be adapted to individual anatomical requirements.

Ceramat has been developing biomaterials and advanced ceramics, with its portfolio including hydroxyapatite, beta-tricalcium phosphate, biphasic calcium phosphate and bioactive glass. These materials have applications in areas such as orthopaedics and oral care. Hydroxyapatite and beta-tricalcium phosphate are calcium phosphate-based materials that resemble the mineral component of natural bone and are used in bone-graft and implant-related applications.

The proposed technology addresses a particular challenge in bone-graft manufacturing: producing grafts with shapes and structures designed for individual patients. While established techniques can produce standard grafts and granules, customised products require more sophisticated design and fabrication capabilities.

Under the project, Ceramat plans to use two 3D-printing approaches — Digital Light Processing (DLP) and extrusion-based printing. DLP-based manufacturing can support the production of complex geometries from digitally designed models, while extrusion-based systems provide another route for fabricating customised structures. The two approaches are intended to provide flexibility for developing both standard and patient-specific graft designs.

The project will also integrate these printing technologies with indigenously manufactured bioceramic raw materials. This could allow the company to expand from conventional bone-graft products into digitally designed and customised biomaterial solutions while building a more integrated domestic manufacturing capability.

A key objective of the initiative is to strengthen India's capacity in high-end medical technology and advanced biomaterials. The government has identified indigenous development of specialised healthcare technologies as an important component of reducing reliance on imported products. The project is therefore positioned as an effort to develop domestic alternatives in the bone-graft and orthobiological segment.

The technology could have relevance across reconstructive orthopaedic procedures and other clinical situations where bone defects require grafting. However, the development and commercialisation of patient-specific grafts would require appropriate technical, safety, regulatory and clinical evaluation before wider clinical adoption.

The TDB-supported project also reflects the growing convergence of digital manufacturing, biomaterials and personalised healthcare. By combining patient-specific digital design with advanced ceramic materials, India is seeking to build capabilities that can support customised medical products while strengthening domestic innovation and manufacturing. TDB Secretary Shri Rajesh Kumar Pathak highlighted the importance of developing specialised healthcare technologies within the country. He noted that combining advanced bioceramics with 3D printing could create opportunities for personalised medical solutions and help reduce dependence on imported products.

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